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<title>08. HEALTH SCIENCES</title>
<link href="http://repository.ou.ac.lk/handle/94ousl/3641" rel="alternate"/>
<subtitle/>
<id>http://repository.ou.ac.lk/handle/94ousl/3641</id>
<updated>2026-09-14T18:02:23Z</updated>
<dc:date>2026-09-14T18:02:23Z</dc:date>
<entry>
<title>EFFECT OF UNANI FORMULATIONS IN MENORRHAGIA – A  CASE STUDY</title>
<link href="http://repository.ou.ac.lk/handle/94ousl/3730" rel="alternate"/>
<author>
<name>Masha, H.A.A.</name>
</author>
<author>
<name>Farzana, M.U.Z.N.</name>
</author>
<id>http://repository.ou.ac.lk/handle/94ousl/3730</id>
<updated>2026-07-15T06:43:26Z</updated>
<published>2025-01-01T00:00:00Z</published>
<summary type="text">EFFECT OF UNANI FORMULATIONS IN MENORRHAGIA – A  CASE STUDY
Masha, H.A.A.; Farzana, M.U.Z.N.
Menorrhagia or Kasrat e Tams is excessive or prolonged menstrual bleeding &#13;
at regular intervals. It is a symptom and not in itself a disease, which &#13;
significantly impacts women's quality of life. While multiple treatments exist, &#13;
some cases remain unresponsive, necessitating alternative approaches. This &#13;
case study evaluates the clinical effect of specific Unani formulations in &#13;
managing chronic menorrhagia unresponsive to previous treatments. A 29&#13;
year-old nulliparous woman residing in Australia had experienced heavy &#13;
menstrual bleeding for five years. She underwent both Ayurveda and &#13;
allopathic treatments for nine months but no relief was obtained. Upon &#13;
returning to Sri Lanka, she sought care at the National Ayurveda Teaching &#13;
Hospital, Borella, where she was admitted from April 6 to April 28, 2025, for &#13;
Unani treatment. Clinical examination revealed pallor; ultrasonography &#13;
indicated an increased endometrial thickness of 20–21 mm without other &#13;
pelvic pathologies. The patient received oral Unani formulations: Qurs-e&#13;
Kehruba one tablet morning and evening, Qurse kustae faulad two tablets &#13;
morning and evening, Safoof-e-Habis-ud-Dam 5gm morning and evening, &#13;
powder of Haleela, baleela and Amla 5gm morning and evening and Majoon&#13;
e- Dabeed-ul-Ward 5gm morning and evening. Additionally, daily sitz baths &#13;
with Post-e-Anar, Roasted Alum and Mazu Sabz decoctions and powder of &#13;
Imly paste on lower abdomen for one month were administered. After &#13;
continued one-month treatment, pallor resolved, and the patient reported &#13;
normal menstrual flow. This case highlights the potential of Unani &#13;
formulations in managing chronic menorrhagia resistant to other treatments. &#13;
As this is a single case report, findings cannot be generalized; further &#13;
controlled studies are justified.
</summary>
<dc:date>2025-01-01T00:00:00Z</dc:date>
</entry>
<entry>
<title>DETECTION OF ANTIBIOTIC-RESISTANT BACTERIA IN  DRINKING WATER SOURCES WITHIN THE COLOMBO  DISTRICT OF SRI LANKA</title>
<link href="http://repository.ou.ac.lk/handle/94ousl/3728" rel="alternate"/>
<author>
<name>Azwer, D.A.</name>
</author>
<id>http://repository.ou.ac.lk/handle/94ousl/3728</id>
<updated>2026-07-15T06:44:11Z</updated>
<published>2025-01-01T00:00:00Z</published>
<summary type="text">DETECTION OF ANTIBIOTIC-RESISTANT BACTERIA IN  DRINKING WATER SOURCES WITHIN THE COLOMBO  DISTRICT OF SRI LANKA
Azwer, D.A.
The rise of antibiotic-resistant bacteria in water distribution systems poses a &#13;
significant risk to public health, particularly in regions such as Sri Lanka, &#13;
where much of the infrastructure was built decades ago and may not meet &#13;
present-day standards for bacterial control. This study aimed to detect the &#13;
presence of antibiotic-resistant bacteria in drinking water sources within the &#13;
Colombo District of Sri Lanka, focusing on two household sampling sites to &#13;
which water is supplied by the National Water Supply and Drainage Board &#13;
(NWSDB).  &#13;
Five biological replicates were analysed using various culturing methods: &#13;
direct spread plating, direct quadrant streaking, and nutrient broth enrichment &#13;
spread plating. This was followed by colony morphology observation, Gram &#13;
staining, biochemical tests: catalase test, oxidase test, methyl-red, and &#13;
Antibiotic susceptibility testing (ABST) via Kirby-Bauer disc diffusion &#13;
method. The antibiotics tested were Gentamycin (10µg), Vancomycin (30µg), &#13;
Ciprofloxacin (5µg), and Ampicillin (10µg). The results were analysed using &#13;
Cowan and Steel’s biochemical guidelines, WHO-listed waterborne &#13;
pathogens, and CLSI guidelines. No fully resistant bacterial species were &#13;
observed across all samples. However, potential intermediate resistance to &#13;
Ciprofloxacin (5µg) by provisional Campylobacter spp. or Pseudomonas spp. &#13;
was observed across an isolate from each sampling site, validating the &#13;
importance of performing routine ABST to monitor bacterial resistance trends. &#13;
Statistical analysis (ANOVA) confirmed no significant variation in antibiotic &#13;
response across the samples. Future work should utilise molecular methods &#13;
such as PCR for bacterial species confirmation and sample collection from &#13;
multiple districts to assess bacterial resistance trends.
</summary>
<dc:date>2025-01-01T00:00:00Z</dc:date>
</entry>
<entry>
<title>DIETARY INTAKE AND NUTRITIONAL STATUS AMONG  ADOLESCENTS IN A SELECTED SCHOOL IN MONARAGALA  DISTRICT, SRI LANKA</title>
<link href="http://repository.ou.ac.lk/handle/94ousl/3727" rel="alternate"/>
<author>
<name>Rathnayaka, R M D J</name>
</author>
<author>
<name>Premasiri, S B W D</name>
</author>
<author>
<name>Bhagya, K A D L</name>
</author>
<author>
<name>Udayakumari, L A M H P</name>
</author>
<id>http://repository.ou.ac.lk/handle/94ousl/3727</id>
<updated>2026-07-15T06:47:08Z</updated>
<published>2025-01-01T00:00:00Z</published>
<summary type="text">DIETARY INTAKE AND NUTRITIONAL STATUS AMONG  ADOLESCENTS IN A SELECTED SCHOOL IN MONARAGALA  DISTRICT, SRI LANKA
Rathnayaka, R M D J; Premasiri, S B W D; Bhagya, K A D L; Udayakumari, L A M H P
This cross-sectional survey assessed dietary intake and nutritional status of 95 &#13;
students, aged 15 to 16 years, from a selected national school in Monaragala &#13;
district, Sri Lanka, at an academic stress period due to ordinary-level examination. &#13;
The study's main objectives are to assess adolescents' dietary intake patterns using &#13;
a seven-day food diary and determined to determine their anthropometric measures &#13;
(BMI, Weight and Height). Participants were trained to complete a structured &#13;
seven-day food diary. Nutrient information was calculated for Sri Lankan food&#13;
based dietary guidelines in order to approximate average daily servings for the &#13;
most significant food groups. The anthropometric data showed that the &#13;
corresponding values for mean BMI, weight, and height for girls and boys were &#13;
19.66 kg/m², 44.20 kg, 150.13 cm, 19.54 kg/m², 47.05 kg, and 154.99 cm. This &#13;
expressed that both genders had healthy levels of BMI. Boys have consumed &#13;
significantly higher numbers of servings of starch and cereals compared to girls (p &#13;
≤ 0.05), with an average of 12.644 servings compared to 11.726 servings for girls. &#13;
Although serving size is lower than the recommended level for fish, eggs, and lean &#13;
meat, the serving size of boys (1.439) is significantly higher (p ≤ 0.05) than that of &#13;
girls (1.096). However, except for cereals and starches, the intake of the remaining &#13;
food groups like pulses and legumes, fruits, vegetables, milk and dairy products, &#13;
sugars and sweets, oily nuts, oils and fats was less than the daily minimum &#13;
requirements for both genders. Notably, there was no significant correlation &#13;
between gender, anthropometric measurements, and serving size in any food &#13;
group. These findings indicate that while both boys and girls are healthy in terms &#13;
of BMI, their dietary patterns are unhealthy, with suboptimal intake of several &#13;
important food groups. Interventions and focused nutrition education are needed &#13;
to overcome these nutritional deficits and promote a better adolescent diet.
</summary>
<dc:date>2025-01-01T00:00:00Z</dc:date>
</entry>
<entry>
<title>ASSOCIATION OF WHITE BLOOD CELL AND PLATELET INDICES  WITH BODY MASS INDEX AMONG FEMALE UNIVERSITY  UNDERGRADUATES IN SRI LANKA</title>
<link href="http://repository.ou.ac.lk/handle/94ousl/3725" rel="alternate"/>
<author>
<name>Senanayake, A.I.</name>
</author>
<author>
<name>Mannage, P.M.N.I.</name>
</author>
<author>
<name>Thennakoon, S.M.</name>
</author>
<id>http://repository.ou.ac.lk/handle/94ousl/3725</id>
<updated>2026-07-15T06:48:32Z</updated>
<published>2025-01-01T00:00:00Z</published>
<summary type="text">ASSOCIATION OF WHITE BLOOD CELL AND PLATELET INDICES  WITH BODY MASS INDEX AMONG FEMALE UNIVERSITY  UNDERGRADUATES IN SRI LANKA
Senanayake, A.I.; Mannage, P.M.N.I.; Thennakoon, S.M.
Obesity is a significant health concern among young adults, yet its impact on &#13;
haematological parameters in young individuals remains underexplored. The present &#13;
study found that a higher body mass index (BMI) was linked to increased white blood &#13;
cell (WBC) count and platelet indices, along with a decreased eosinophil percentage, &#13;
suggesting obesity-related haematological alterations even in healthy undergraduates. &#13;
This cross-sectional study was conducted among 91 healthy females aged 18-25 after &#13;
obtaining ethical approval from the Ethics Review Committee of the Institute of &#13;
Biology, Sri Lanka (ERC IOBSL 380/11/2024). Participants were required to complete &#13;
a self-administered questionnaire to select healthy individuals without a diagnosed &#13;
chronic illness. Participants were excluded if they smoked, consumed alcohol, were &#13;
pregnant, recently ill, had haematological disorders, donated blood within the last six &#13;
months, or used medications/supplements affecting haematological parameters. &#13;
Anthropometric measurements were employed to calculate BMI. Height was recorded &#13;
using a standard stadiometer, with participants standing upright, their heels, hips, and &#13;
head aligned against the measuring surface. Body weight was assessed using a &#13;
calibrated electronic scale. Participants were divided into four groups according to &#13;
Asian BMI classification: underweight (BMI&lt;18.5kg/m2), normal weight (BMI=18.5&#13;
22.9 kg/m2), overweight (BMI=23.0-24.9 kg/m2) and obese (BMI≥25.0 kg/m2). The &#13;
full blood count analysis was performed using an automated haematology analyser &#13;
(Mindray BC-20, Shenzhen, China). Correlation analysis was performed using Pearson &#13;
or Spearman coefficients, with p-values &lt; 0.05 considered statistically significant. &#13;
Statistically significant positive correlations were observed between BMI and total &#13;
WBC (r =0.434, p =0.000), absolute granulocyte count (r =0.362, p =0.000), platelet &#13;
count (PLT) (r =0.326, p =0.002), and plateletcrit (PCT) (r =0.383, p =0.000), whereas &#13;
eosinophil percentage showed a significantly negative association (r = -0.272, p &#13;
=0.009). Several WBC and platelet indices, including absolute lymphocyte count (r &#13;
=0.032, p =0.763), monocyte percentage (r = -0.187, p = 0.077), mean platelet volume &#13;
(r = 0.002, p = 0.982), and platelet distribution width (r = 0.048, p = 0.653), did not &#13;
demonstrate statistical significance with the BMI. Future research should explore &#13;
causal relationships between BMI and haematological alterations in more diverse &#13;
populations. Therefore, the present study contributes to understanding obesity induced &#13;
haematological alterations and provides a basis for future longitudinal investigations.
</summary>
<dc:date>2025-01-01T00:00:00Z</dc:date>
</entry>
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